Origin of life: The RNA world

@article{Gilbert1986OriginOL, title={Origin of life: The RNA world}, author={Walter Gilbert}, journal={Nature}, year={1986}, volume={319}, pages={618-618}, url={https://api.semanticscholar.org/CorpusID:8026658} }
L'auteur postule un systeme, auto-replicatif a l'origine uniquement compose de molecules d'ARN.
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2,291 Citations

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8 References

Catalytic activity of an RNA molecule prepared by transcription in vitro.

The RNA moiety M1RNA of ribonuclease P from Escherichia coli and the unprocessed transcript prepared in vitro of the gene for M1 RNA can both perform the cleavage reactions of the canonical enzyme in the absence of the protein moiety.

The intervening sequence RNA of Tetrahymena is an enzyme.

The shortened form of the self-splicing ribosomal RNA intervening sequence of Tetrahymena thermophila acts as an enzyme in vitro that can act as an RNA polymerase, differing from the protein enzyme in that it uses an internal rather than an external template.

Self-splicing RNA: implications for evolution.

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

Biochemistry: Polyribonucleic acids as enzymes

On the origin of RNA splicing and introns

The origin of genetic information.